A vaccine developed by the University of Washington
researchers proves effective in preventing the growth of HER2 tumour
cells that have led to numerous deaths worldwide. Results of phase one
human trials show a promising outcome.
Researchers at
the university's School of Medicine (UWSM) in Seattle have been working
on developing a breast cancer vaccine for over two decades and they have
finally succeeded in generating a strong immune response against the
human epidermal growth receptor 2 (HER2) tumour cells.
Half
of the people with HER2-positive breast cancer usually don't survive
more than five years after being affected. However, during the 10-year
assessment period, 80 percent of the vaccine participants survived.
Following
this success, the team is now conducting phase II trials that may lead
to treating breast cancer. These results have sparked hopes that the
vaccine may also lead to the cure for other types of cancerous cells.
Here is a testimony from a cancer survivor who received the new vaccine.
Stephanie Gangi, a 66- year-old author from the US, shares the story of her survival with The Telegraph: "I have some resistance to tempting fate with any definitive proclamations, but I am hopeful, and I feel great".
Gangi
was treated for breast cancer in 1999 first. Fifteen years later, her
cancer returned and spread to her breastbone. By 2021, a big size tumour
appeared on her adrenal gland.
But last week, Gangi had
what she describes as a "nice and boring" scan showing no signs of
cancer. The giant tumour has gone, and she has been cured, thanks to
this experimental vaccine.
"This is the first time
we've seen such an amazing response," says Samik Upadhaya, assistant
director of scientific affairs at the Cancer Research Institute in the US to The Telegraph.On the other hand, Dr. Mary (Nora) L. Disis,
associate dean of the UW School of Medicine, believes that there is a
good probability that the vaccine will be utilised in clinics by 2030
and that it has the potential to be a groundbreaking discovery in the
realm of modern medicine.
“Because this was not a
randomized clinical trial, the results should be considered preliminary,
but the findings are promising enough that the vaccine will now be
evaluated in a larger, randomized clinical trial,” she added in a statement published UW Medicine webpage.
Source: TRTWorld and agencies
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